No adverse effect has been reported when taken in accordance with the suggested use. In the clinical study of excessive intake (4,050 mg of shiitake mushroom mycelia extract per day - threefold to nine-fold intake of the suggested use), some adverse effects such as nausea, diarrhea, bloating, headache, fatigue and foot cramps are reported. Although these symptoms are generally mild and tolerable, please follow the suggested use.
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